Flunitrazepam, also known as Rohypnol among other names, is an intermediate-acting benzodiazepine used in some countries to treat severe insomnia and in fewer, early in anesthesia.
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Flunitrazepam is lipophilic and is used hepatically through oxidative pathways. The compound CYP3A4 is the primary catalyst in its stage 1 digestion in human liver microsomes. Flunitrazepam with different benzodiazepines can prompt medication dependency and benzodiazepine withdrawal syndrome.
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